RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
SNHG7
RNA ID
RNA Type
lncrna
Alteration Pattern
dysregulation
Species
homo sapiens
Detection Methods
qRT-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
DNMT3A
Pathway
NA
PubMed ID
Title
"LncRNA-SNHG7/miR-29b/DNMT3A axis affects activation, autophagy and proliferation of hepatic stellate cells in liver fibrosis"
Year
2020
Function
"Inhibition of lncrna-snhg7 can inhibitliver fibrosis. This is partly due to snhg7 acts as a competitive endogenous rna (cerna) to affect the expression of dnmt3a, a downstream target gene of mir-29b, by binding to mir-29b, thereby affecting the activation, autophagy and proliferation of hscs."